The name Alexis is both semantically and culturally linked to the name Alexander (or Alexandra/Alexandria) which is actually of Greek origin. Therefore the name Alexis doesn't have any specific meaning in Italian.
Meaning of the name Alexis
Seeing as the name is linked to Alexander, Alexis also shares a similar meaning of 'defender' or 'defender of men'.
The name was originally only used for boys (in Greece it is still more commonly a male name) whereas in recent times its popularity as a name for females has surged globally. The name is used in English, French, German and Greece, and is spelled Alexei in Russian.
Variants of the name Alexis
One of my favorite things about the name Alexis is that it has so many variants and similar names. This is great when you need to use a pseudonym or pen-name, or simply if you fancy using a nickname with friends or family.
Names that are similar to Alexis include:
Famous people with the name Alexis
Famous people with the name Alexis include musician Alexis Korner, singer Alexis Jordan, actress Alexis Biedel and footballer Alexis Sanchez
You can tell right away by the lack of Italians that feature in this section that the name Alexis isn't as common in Italy as it is in other European countries. If you're looking for a notable Italian-born Alexis. Then one rather clever answer would be the ancient Greek poet Alexis. He was born in 394 BC in Thurii, Magna Graecia which sounds Greek enough but is actually in what is modern day Calabria, Italy.