What Does Poly Mean In The Medical World?


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Akshay Kalbag answered
The word poly, in the medical world, refers to the term Poly (ADP-ribose) polymerase, which is abbreviated as PARP. The term PARP is defined as a protein, which is involved in a number of cellular processes. These cellular processes mainly involve DNA repair and the programmed death of the cells in the human body.

Poly (ADP-ribose) polymerases are defined as those proteins which are involved in many processes in the cells of the human body. These enzymes have the capability to make a polymer of ADP-ribose (which is abbreviated as PAR) from NAD, which is nicotinamide adenine dinucleotide.

The polymer can be degraded by an enzyme which is highly specialised. This highly-specialised enzyme is called PARG, which is the abbreviation for poly (ADP-ribose) glycohydrolase. There is another enzyme which has recently been discovered. This new enzyme, which is not related to PARG, can degrade PAR. This new enzyme is known as ARH3.

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