Having a high Mchc means the high concentration of corpuscular haemoglobin in the red blood cells, and can be indication of a rare congenital disorder called hereditary spherocytosis. Also the sickle cell disease, and homozygous haemoglobin C disease can be reasons for high Mchc. It is also possible to have a high Mchc level due to a lack of vitamin B12 of folic acid in the body. The term Mchc stands for the mean corpuscular haemoglobin concentration. It is the average measurement of the haemoglobin concentration in packed red blood cells and the Mchc count is a part of a standard blood count test. The increased levels of the Mchc and the resulting concern that it may indicate the condition hereditary spherocytosis means that the red blood cells are spherical instead of the normal oval shape of the cells and is also the increase in haemolysis or the breakdown of red blood cells. It is also suggested that lipemia and cellular dehydration syndromes can also lead to increase in Mchc. The Mchc is calculated by the multiplying of the haemoglobin by one hundred and then dividing the resulting number by the amount of the packed red blood cells. The haemoglobin is a substance which is within the blood that transports oxygen to the cells in the body from the lungs to the rest of the organs. The cell within a human body is the slightest and most rudimentary element of life which is capable of surviving by itself. The normal level of the Mchc is around 28% to 36% for adults and 32% to 34% for children, and therefore if discovered to be over 36% it is considered to be too high and is a result of the presence of spherocytes in the blood. To contain abnormally high levels of haemoglobin is known as having too much Spherocytes in the blood cells.
