Like in the song? I always thought he meant like an orange soda...
Hahaha
What Does An "Orange Crush" Mean In Drug Terms?
In the song orange crush is a nickname for agent orange, a chemical used in the vietnam war. In drugs, its a nickname for some cold medicines.
In the song it says I got my spine I got my orange crush and spine means you have bravery and people say orange crush means bravery I don't know what it means in drug terms.